As such, Xavier's X-Men often oppose Lensherr's Brotherhood of Mutants in working towards their respective goals. He is often depicted as kind, empathetic and wise in his ability to relate to his mutant brethren, and believes in a future where his race is fully welcomed into society at large, contrasted by his former friend Erik Lensherr, who works to establish mutants as dominant over humans, due to his jaded views on their co-existence being amplified by his experiences as both a mutant and Holocaust survivor during World War II.

With the assistance of several of his school's alumni, he eventually forms and leads a mutant strike force known as the X-Men, dedicated to carrying out his initiative for a peaceful co-existence between mutants and humanity, the latter of whom express significant phobia towards them. In the film series' continuity, Xavier is a mutant activist and founder of the Xavier School for Gifted Youngsters, intended to house displaced or discriminated mutants while acting as an educational and training ground for cultivating their powers. Professor Charles Francis Xavier, also known simply by his codename Professor X, is a fictional character primarily portrayed by Patrick Stewart, James McAvoy, and Harry Lloyd in 20th Century Fox's X-Men franchise and the Marvel Cinematic Universe (MCU) franchise produced by Marvel Studios, based on the Marvel Comics character of the same name created by Stan Lee and Jack Kirby.

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